منابع مشابه
Adjusting for Urinary Creatinine Overestimates Arsenic Concentrations in Diabetics.
BACKGROUND/AIMS: Arsenic (As) is linked to insulin resistance in animal studies, but the effect of low-level As exposure on the prevalence of diabetes in humans is uncertain. An optimal method to report inorganic As in humans has not been established. Measurements of As in spot urine are usually adjusted to creatinine (Cr). However, urinary Cr is an independent variable in diabetes. Our aims ar...
متن کاملCreatinine, Arsenic Metabolism, and Renal Function in an Arsenic-Exposed Population in Bangladesh
Kidney disease is emerging as an arsenic (As)-linked disease outcome, however further evidence of this association is warranted. Our first objective for this paper was to examine the potential renal toxicity of As exposure in Bangladesh. Our second objective relates to examining whether the previously reported positive association between urinary creatinine (uCrn) and As methylation may be expl...
متن کاملCreatine and creatinine metabolism.
The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology. Very recently, a series of new discoveries ...
متن کاملRelationship of Creatinine and Nutrition with Arsenic Metabolism: Smith et al. Respond
potentially sparing SAM for methyla tion of other substrates such as As. We are currently testing this hypothesis in a randomized controlled trial of creatine supplementation. In addition, as Basu et al. (2011) noted, and as we have previously reported (Gamble and Liu 2005), one implication of the observed association between uCr and As methylation capacity is that urinary As should not be expr...
متن کاملUrinary creatinine and survival in CKD.
Low muscle mass is associated with risk of CKD progression, cardiovascular disease events, and mortality in avarietyof settings (1). It iswidelyhypothesized that these associations may be confounded by conditions associated with low muscle mass, including frailty, poor physical fitness, poor nutritional status, and greater comorbidity. However, lowmuscle is also hypothesized to worsen insulin r...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2005
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.113-a442a